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For example, METH and cocaine disrupt monoaminergic signaling, whereas ketamine and nitrous oxide impair glutamatergic neurotransmission

doi: 10.1155/2015/825802 61 HsuCNTainYL

To this purpose, in vitro and in vivo assays were employed to test the existence of succinylation modification on GCLC, and the influence on its enzymatic activity was further determined by quantificationally measuring the cellular GSH levels

A cell culture study found that proanthocyanidin-rich grape seed extract protected heart muscle cells from doxorubicin-induced toxicity without interfering with the antiproliferative effect of doxorubicin on breast cancer cells (Li, Liu 2010)