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S., Khandelwal, P

A fully automated, multiplexed small scale anti-fibrotic drug screen identified eleven compounds that were able to revert the fibrotic phenotype, with two compounds also able to restore hepatocyte function and modulate vascular plexus morphology

GPX1 KO mice developed normally, indicating that the lack of antioxidant defenses could be compensated for by other proteins, or that oxidative stress under normal conditions did not cause any harm