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(2022) found that calcium channel blockers such as nifedipine, as well as antioxidants such as MitoQ, curcumin, and apigenin, alleviated the memory dysfunction and cognitive deficits in AD mouse models by intervening in mitochondrial dysfunction

[DOI] [PubMed] [Google Scholar] 174.Glpen J., Breedvelt JJ F., van Dis EA M., Geurtsen G.J., Warren F.C., van Heeringen C., Hitchcock C., Hollndare F., Huijbers M.J., Jarrett R.B., et al

Abbreviations CKD: Chronic kidney disease TECs: Tubular epithelial cells UUO: Unilateral ureteral obstruction IRI: Including ischemia-reperfusion injury Fer-1: Ferrostatin-1 GPX4: Glutathione peroxidase 4 ACSL4: Acyl-CoA synthetase long-chain family 4 LPCAT3: Lysophosphatidylcholine acyltransferase 3 TFRC: Transferrin receptor protein 1 DMT1: Divalent metal transporter 1 FPN: Ferroportin CTGF: Connective tissue growth factor PDGFB: Platelet-derived growth factor subunit b FGF2: Fibroblast growth factor 2 4-HNE: 4-hydroxynonenal MDA: Malondialdehyde References Webster AC, Nagler EV, Morton RL, Masson P