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BPC 157 appears to play a role in the braingut axis and has central effects [26], and BPC 157 administration can also counteract central disturbances (i.e., brain swelling, intracranial hypertension), which may likely appear in the rats subjected to permanent, simultaneous occlusion of the superior mesenteric vein and artery (i.e., increased intra-abdominal pressure and increased intracranial pressure) [27]

More research is needed before recommending spermidine-rich or polyamine-modified diets to individuals with existing malignancies 21 , 135

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Side effects were dose-dependent and transient