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Shields CL, Shields JA, Kiratli H, et al

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Experts Recommendations for Therapeutic Landscapes The extended use of metformin, a key player in preventing type 2 diabetes among individuals with prediabetes, has been associated with vitamin B 12 deficiency, particularly concerning for specific subgroups such as those with a BMI of 35 kg/m 2 , individuals below the age of 60, and women with prior gestational diabetes mellitus [46]

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LC supplementation has been shown to have beneficial effects in the management of PCOS, amenorrhea, and endometriosis [48]

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