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One of the main enzymes with desaturase activity is the stearoyl-CoA desaturase-1 (SCD1), localized at the ER, catalyzing the biosynthesis of MUFAs, (i.e., palmitoleate and oleate) from their SFA precursors (i.e., palmitate and stearate) [55]

The capping modification of mRNA, which rigorously follows subgenomic mRNA synthesis, is essential for viral translation and propagation, mRNA protection and escape from host immune response 125,126