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Description

Adamko, D.J., Yost, B.L., Gleich, G.J., Fryer, A.D

Cyclic 3,5adenosine monophosphate (cAMP) signaling in the anterior pituitary gland in health and disease

Challenges in scalable, GMP-compliant manufacturingparticularly batch-to-batch variability in encapsulation efficiency (2194% for PLGA NPs)and long-term biocompatibility assessments (e.g., hepatosplenic accumulation, PEG immunogenicity) remain unresolved