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Allosteric inhibition of phosphofructokinase-1 by citrate forms the basis of the Pasteur effect, the absence of which is critical for understanding the Warburg effect, i.e., aerobic glycolysis, a general feature of not just tumor cells 99 , but also healthy proliferating cells 100 such as lymphocytes and stem cells 101,102

[DOI] [PubMed] [Google Scholar] 213.Campbell U.B., Walker A.M., Gaffney M., Petronis K.R., Creanga D., Quinn S., Klein B.E., Laties A.M., Lewis M., Sharlip I.D

No, you will not get sick simply because you stopped taking the supplement

interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-), IB is phosphorylated at Ser32 and Ser36, resulting in the rapid ubiquitination by the proteosome in the dependent manner to release NF-B [5, 6]