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This shift triggers mitochondrial outer membrane permeabilization (MOMP), resulting in cytochrome c release and the initiation of caspase-dependent apoptosis [215, 216]

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NOX1 is essential for TNF-induced intestinal epithelial ROS secretion and inhibits M cell signatures

Rotenone is highly toxic to fish and certain invertebrates and has in the recent years been used to exterminate invasive fish species and parasites in Norwegian rivers (Sandodden et al