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Signal Transduction Multiple studies indicate that GPX4 plays a significant role in the mechanisms of pain signal transduction

2.2 Clinical diagnosis To date, there is a lack of established diagnostic standards for BIPN, which leads to a frequent underestimation due to patient underreporting and insufficient assessment by physicians (Park et al., 2019)

PLoS One 7 , e41281 (2012)

An increasing number of studies have documented that failed lysosomal function is closely related to the occurrence and development of neurodegenerative diseases, including Gaucher disease, hereditary spastic paraplegias, and Alzheimers disease (AD) 18,123,124,125