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Estimates suggest that tobacco use causes about 80,000 cases of gastric cancer annually (11% of all estimated cases) ( 4 Oxidative stress in gastric cancer 4.1 Gastric carcinogenesis Under oxidative stress, increased ROS in cells may harm tissues and trigger carcinogenesis, especially in the gastrointestinal system ( Figure 3 )

10.1016/j.omtn.2019.01.013 94 HaywardS

The sensitivity of R 4 parameters ( k p4 ) with respect to model OCR output is in good accordance with the AIC/BIC analysis, confirming the need for the R 4 reaction, which is present in both the triad and the comproportionation models, but not in the reduced model