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Activation of these proteins induces a variety of responses, including cell proliferation, differentiation, and apoptosis in the epidermis [37,38]

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10.1016/j.expneurol.2012.08.023 Summary Keywords neuropathic pain, oxidative stress, inflammation, mitochondrial dysfunction, TRP channels, antioxidants Citation Carrasco C, Nazirolu M, Rodrguez AB and Pariente JA (2018) Neuropathic Pain: Delving into the Oxidative Origin and the Possible Implication of Transient Receptor Potential Channels

Notably, it can induce oxidative stress in endothelial cells, initiating inflammatory responses (42)