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Because of this, patients are observed for at least 30 minutes after each infusion

Patients with renal impairment, renal failure , hepatic disease, diabetes mellitus, systemic lupus erythematosus (SLE), congestive heart failure, rheumatoid arthritis, edema, extracellular volume depletion (i.e., hypovolemia or dehydration), sepsis

For patients who would use both peptides anyway, the Wolverine Blend simplifies the protocol

A review by Paul and Brady (2017, Integrative Medicine) noted that methylcobalamin may produce faster improvement in neurological symptoms for some individuals