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AIDS and AIDS-related conditions)

Both events are expected to increase the pool of free fatty acids, which ACSL3 metabolizes into Fatty Acyl CoAs, thereby activating the fatty acid for downstream metabolism

On the other hand, if uncontrolled, the enormous increase in the ROS levels inserts negative oxidative influences on cellular proteins, lipids and nucleic acid, ultimately leading the affected cell towards controlled programmed cell death (PCD) [89]