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Large goitre as a maladaptation to iodine deficiency

10.1016/j.mcna.2005.06.009 Med

The Good Face Project

Together, these findings indicate that while strong oxidants, such as H 2 O 2 , favor irreversible thiol overoxidation and suppress disulfide chemistry, reactive nitrogen species provide a physiologically relevant pathway for disulphide cross-linking of TTR