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Description

Patients experiencing persistent diarrhea should be monitored for signs of dehydration and electrolyte disturbances, particularly potassium and magnesium depletion

, Pchitskaya E., and Bezprozvanny I

In the apo structure of ICL1, the active site loop (residues 185196) preferentially maintains an open and solvent-accessible conformation [162], where Cys191 is positioned at a considerable distance away from other catalytic residues