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A significant decrease in PKC activity in the cytosol and membrane fractions of prefrontal and temporal cortex was present in participants with bipolar disorder, but not schizophrenia, affecting all classic PKC isoforms (PRKCA, PRKB-I, PRKB-II, PRKCG) (Pandey et al., 2020)

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This promotes the transfer of a hydride ion (H ) from C-3 of the substrate to C-4 of the nicotinamide ring in NADP + , yielding NADPH

[DOI] [PMC free article] [PubMed] [Google Scholar] 88.Tang LJ, Luo XJ, Tu H, Chen H, Xiong XM, Li NS, et al