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10.1016/j.jaad.2016.10.048 175 SagiL.TrauH

Hydronephrosis can occur in one or both kidneys, and symptoms vary accordingly

Evidence for the involvement of N-methylthiourea, a ring cleavage metabolite, in the hepatotoxicity of methimazole in glutathione-depleted mice: structure-toxicity and metabolic studies

More importantly for this discussion, it acts as a cofactora "helper" moleculethat is absolutely necessary for the enzymes that build and stabilize collagen