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The company itself also funded some of the research, creating an obvious potential bias

59 Shafei reported that BCAT1 inhibited the Ras/ERK pathway and activates PI3K/AKT pathway through insulin/IGF-1, ultimately promoting the expression levels of FOXO3a and Nrf2 and regulating the proliferation, migration, and invasion in triple-negative breast cancer (TNBC)

PMID 15598662

Among these approaches, recent studies have focused on intercellular communication through EVs released by human induced pluripotent stem cells (hiPSCs) cultured under 5% O 2 (EV-H5)