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Inositol - Dietary supplement that breaks down sugars to use as energy

Randomized controlled trials have demonstrated 60 to 100% reductions in NTD cases when women consumed folic acid supplements in addition to a varied diet during the month before and the month after conception

[1] [2] These include reduced caloric intake due to appetite suppression, gastrointestinal side effects leading to decreased food intake, delayed gastric emptying, changes in blood glucose levels, and the metabolic adjustments associated with significant weight loss

Its an essential nutrient that the body needs but cannot produce on its own, so it must be obtained through diet or supplements