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Description

The activation of the HIF-1 gene locus is triggered by the interaction between transcription factors, such as STAT3 and NF-B, and their promoter regions [Figure 1]

All samples were lysed with 3 flash-freeze-thawing cycles using 80C and 37C, respectively

These movements likely avoid clashes between CRBN and the extended conformation of ENL Q41 that is seen in the apo crystal structure (Fig

Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate