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When to Consider Oral Vitamin B12 Supplements For Maintenance or Mild Deficiency : If youre generally healthy and need B12 supplementation to maintain healthy levels or correct a mild deficiency, oral supplements are a convenient and cost-effective option

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Regression models demonstrated that participants with deficient-low B12 status at baseline had a significantly higher likelihood of incident depression 4 years later (OR 151, 95 % CI 101, 227, P = 0043)