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Description

Selection of an efficient AAV vector for robust CNS transgene expression

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doi: 10.1016/j.omtn.2021.08.030 433 AkalinAKormakssonMLiSGarrett-BakelmanFEFigueroaMEMelnickAet al

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For example, dasatinib, a senolytic agent that inhibits tyrosine kinase (TK) activity and regulates the SASP, has been shown to promote the differentiation of CD4 + T cells toward a more juvenile phenotype

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