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Shortall et al., 2021)

Lacking modular design principles like bifunctional CIPs, most molecular glues have been discovered through retrospective mechanism-of-action studies 1,2

Making the decision: IV first or peptides first

References NIH Office of Dietary Supplements: Vitamin B12 Fact Sheet for Health Professionals National Heart, Lung, and Blood Institute: Vitamin B12-Deficiency Anemia FDA: Advises Consumers Not to Inhale Nitrous Oxide Products, March 2025 Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study, Journal of Clinical Endocrinology and Metabolism UCSF: B12 Levels Within the Normal Range Linked to Cognitive Decline, Annals of Neurology Excess Folic Acid and Vitamin B12 Deficiency: Clinical Implications