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Mice were given access to food and tap water ad libitum

The dose of fentanyl we chose for this study (75 g/kg, IV) elicited a robust decrease in minute ventilation (approximately 50% over a period of at least 60 min) and so represents a substantial level of ventilatory impairment by which to examine the effects of the 100 mol/kg dose of GSHee

However, ignoring a sprained thumb with the hope that it will heal on its own may lead to long-term problems, including: Chronic instability Weakness Arthritis If these late complications develop, you may need surgery to rebuild the ligament using tissue from your upper arm