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Another important function of GHK-Cu is its ability to regulate inflammatory markers

In the ATG5-ATG7-NCOA4 pathway, the process of ferritin-associated autophagy that is mediated by NCOA4 can increase the content of unstable iron in cells, thus promoting ferroptosis 33

These findings highlight the potential of dual CYP17A1 and HDAC6 inhibition as a promising strategy to overcome resistance in GBM therapy, offering a new avenue for more effective treatments