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This review started with an evolutionary perspective regarding plants and microbes, an interaction that has always been present, to the benefit of both members of the partnership

doi:10.1159/000013455

While surgical denervation does not adversely affect expression of Mist1 (Fig 3B and E), muscarinic stimulation is sufficient to increase MIST1 in human cultures and suggests that although not required for acinar cell identity, acetylcholine/muscarinic signaling may act as a positive regulator of the secretory program