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In this study, the ratio of Bcl-2/Bax was observed decreased after NAC and BSO co-treatment, which could also be reversed by Notch2 overexpression (Fig

ChoiIYPiccioLChildressPBollmanBGhoshABrandhorstSet al

Graphical abstract Similar content being viewed by others Literature search Online research was carried out using medical research databases Google Scholar, NCBI, and PUBMED with the following terms: cyclophosphamide, cyclophosphamide pharmacokinetics, cyclophosphamide pharmacodynamics, cyclophosphamide neurotoxicity human, cyclophosphamide neurotoxicity animals, cyclophosphamide cognitive impairment, cyclophosphamide oxidative stress, cyclophosphamide inflammation animals, cyclophosphamide apoptosis