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[DOI] [PubMed] [Google Scholar] 31.Petri S., Krner S., Kiaei M

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In addition, studies of resistance to cereblon-based PROTACs have shown that this may result from downregulation of transcription of E2 ubiquitin conjugating enzyme UBE2G1 196

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It's in the assumptions

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The ferryl oxidation state of iron is very unstable, therefore these high-valence Hb forms are short-lived intermediates that decay quickly (60)

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