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These results suggested L-carnitine through the AKT/FOXO3a/MaFbx axis and p70S6K (Fig

The main pathophysiological changes in DKD kidney, include podocyte damage, thickening of the GBM, interstitial fibrosis, and hyalinosis of blood vessels 39 , as well as mitochondrial dysfunction in the podocytes 16

Fibroblast growth factor receptor (FGFR) pathway FGFR, a member of the RTK family, comprises four principal isoforms: FGFR1, FGFR2, FGFR3 and FGFR4 (164)

Activation of p38 and N-acetylcysteine-sensitive c-Jun NH2-terminal kinase signaling cascades is required for induction of apoptosis in Parkinsons disease cybrids