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[32] observed, in an experimental model (rats), that exhaustive exercise induces an increase in macrophages functionality (phagocytosis and H 2 O 2 production), as well as an augment in glutamine consumption and metabolism in these cells, indicating the importance of glutamine for macrophages functionality in the post-training period and suggesting a possible role for glutamine supplementation to individuals involved in exhaustive exercises [32]

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Therefore, ozone therapy emerges as a potent yet intricate intervention, necessitating further in-depth scientific scrutiny

Available at: US Department of Health and Human Services, Food and Drug Administration, 21 CFR Part 101 [Docket No