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Dumitrescu L, Papathanasiou A, Coclitu C, Garjani A, Evangelou N, Constantinescu CS, Popescu BO, Tanasescu R (2023) An update on the use of sphingosine 1-phosphate receptor modulators for the treatment of relapsing multiple sclerosis

[39] HIF1 can bind to one of the several hypoxia response elements (HREs) in the MET promoter

We measured the fluorescence intensity in treated mice and found that the combination therapy of metformin and simvastatin significantly reduced tumor fluorescence intensity compared to the individual use of metformin and simvastatin (Fig