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The definition of deficiency is a reading below 148 pmol/L

DDP, cisplatin

Mechanistically, during the early stages of bacterial infection, cells elevate unstable intracellular iron levels by activating two iron metabolism pathways: nuclear factor erythroid 2related factor 2/heme oxygenase-1 (Nrf2/HO-1) and ferritin/NCOA4

Furthermore, this depletive process can be rescued after estrogen supplementation, increasing the number of spines (Luine and Frankfurt, 2013) and spine synapses in CA1 (Woolley and McEwen, 1992)