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It works best as part of a broader plan that includes appropriate exercise, joint supplements, weight management, and veterinary oversight

This is particularly the case for the sublineages of the Omicron variant, due to its ability to evade antibodies from prior exposure to both earlier variants and vaccines [16, 34, 35]

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Nonetheless, cycling usage (e.g., eight weeks on, four weeks off) and medical supervision are recommended, especially for those with pre-existing kidney or liver conditions