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Smoking affects symptom improvement in schizophrenia: a prospective longitudinal study of male patients with first episode schizophrenia Schizophrenia Factors promoting tobacco use in schizophrenic patients: IV. Download Scientific Diagram The Intrinsic Receptor Deficit In the general population, chronic smoking leads to an upregulation of 42 nicotinic receptors. In schizophrenia, this compensatory upregulation is impaired. This suggests an intrinsic defect in the Nicotine: Good or Bad for Schizophrenia Symptoms?
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