risks of l-carnitine Beneficial effects supplementation for weight management in overweight and obese adults: An updated systematic review and dose-response meta-analysis of randomized controlled trials What are the adverse effects

doi: 10.1186/s12967-017-1175-y 141

Early studies from the late 1990s reported that supplementation at 12 grams per day improved mood and reduced fatigue in patients with major depressive disorder, as evidenced by reductions in Hamilton Depression Rating Scale scores by about 2030% over 48 weeks [5]

Further research is necessary to understand the exact molecular mechanisms linking carnitine transporters and reproductive health, which could lead to novel treatments for both male and female infertility

However, studies evaluating the role of omega-3 PUFA-based nutraceuticals in the setting of thyroid disorders, reached inconclusive results [133]