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Methionine in turn is required for the synthesis of S-adenosylmethionine, a methyl group donor used in many biological methylation reactions, including the methylation of a number of sites within DNA, RNA, and proteins ( Figure 1 ) (3)

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Consequently, while the reductionist classical view might be valid for describing ordinary solution chemistry performed in laboratory glassware (the surrounding solvent acting as a heat bath for the reactants), it is inadequate when considering protein structure and function within the cellular cytoplasm: for there is nothing random, chaotic, or statistical about cellular biochemical events