Propargyl-Acetyl-Val-Cit-PAB(m-PEG8) best Contains an E3 ligase ligand

Contains an E3 ligase ligand substituted with piperidine

Product Name Thalidomide-5'-O-PEG6-OH Synonyms CAS Number n/a Related CAS Molecular Formula C25H34N2O11 Molecular Weight 538

43 SMILES Cl

5 SMILES CC(C)(C)OC(=O)N1CCN(CCN2CCN(CCN)CC2)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Propargyl-Acetyl-Val-Cit-PAB(m-PEG8) best Contains an E3 ligase ligandSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned through selection