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IKK, the catalytic subunit essential for canonical NF-B activation, directly interferes with insulin signaling by functioning as a serine kinase that phosphorylates IRS-1 on inhibitory sites (5662)

Reducing collagen deposition: In chronic fibrosis, TGF-/Smad persistently signals, which leads to fibrosis and contributes to the progression of cancer

Access this article Similar content being viewed by others Data availability The data used to support the findings of the present study are available from the corresponding author upon request