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Postmortem studies indicate that KYN metabolism might also be modified in AD as increased concentrations of KYNA were found in the basal ganglia of AD patients (Baran et al., 2011), indicating that an upregulation of KYNA might be an endogenous protective response

Dimethylaminomicheliolide is a novel chemotherapeutic agent that induces apoptosis and autophagy by adjusting the ROS/MAPK signaling pathway and inhibiting the Akt/mTOR signaling pathway to treat gliomas (Wang et al., 2019)

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Efficacy and safety of oral lacosamide as adjunctive therapy in adults with partial-onset seizures