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But its something to keep an eye on if successful, these developments would reduce the burden on patients and in vivo editing could make treatment much more widely accessible

FAD: flavin adenine dinucleotide Pathogenesis of riboflavin or flavocoenzyme deficiency and mitochondrial dysfunction Riboflavin deficiency or defects in the production of its flavocoenzymes FAD and FMN can lead to disruption of the RC, consequently mitochondrial dysfunction, and increased production of ROS, overwhelming the cellular antioxidant mechanisms

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