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Endometriosis is frequently linked to increased oxidative stress [23], which arises from a dysregulated balance between the production of reactive oxygen species (ROS) and the bodys antioxidant defense mechanisms [24]

Our study finds that in the presence of Ran-GTP and RanBP1, importin retains a low affinity for FG-nups and can hold onto the cargo due to the extended position of the C-terminal HEATs 1119, suggesting the possible formation of a larger assembly consisting of the importin complex (importin :1:NLS-cargo) associated with Ran-GTP:RanBP1