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23 In fact, since 2010 the number of deaths caused by a combination of opioids and cocaine has increased more than fivefold

These co-amendments promote the proliferation of hydrocarbon- and pesticide-degrading bacteria, thereby increasing enzymatic activity involved in contaminant transformation

The synthesis and catabolism of GSH and its adducts occurs by a regulated series of enzymatic and plasma membrane transport steps that are collectively referred to as the -glutamyl cycle (Figure 1) (Meister and Tate, 1976