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This cascade of oxidative stress can lead to cellular dysfunction and damage, significantly impacting various tissues and organs [174, 175]

Pediatr Nephrol 7:159162

Since Nrf2 serves as a platform of interrelation between NF-B and ER stress (Figure 3), special attention has been paid to this transcription factor to better define its possible contribution to oxidative stress of the vulnerable plaque (141) (Figure 2C)