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10.1185/03007995.2014.938731 94 MoherD.LiberatiA.TetzlaffJ.AltmanD

Predictive biomarkers, particularly those linked to key regulatory axes such as NRF2/p62, COX7A1 or USP13, require urgent discovery and clinical validation to reliably predict sensitivity to ferroptosis inducers or autophagy modulators

SaeediBJLiuKHOwensJAHunter-ChangSCamachoMCEbokaRUet al

In cohort 3, 16 eyes showed improvement in MMS and heatmaps (Figure 7, AD, and Supplemental Figures 3438, 4046, and 4849) and 2 eyes showed little change or worsening (Supplemental Figures 39 and 47)