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Consistent with these findings, HIF-1 and NRF2 expression levels are mutually associated, and high levels of these transcription factors correlate with poor outcomes in glioblastoma patients 90

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Before CoQ 10 emerged as a ferroptosis suppressor, it was primarily viewed as an essential electron carrier in the mitochondrial electron transport chain (ETC), shuttling electrons from complexes I/II to complex III to maintain oxidative phosphorylation 18

On the other hand, oral glutathione capsules are a convenient and accessible option for everyday use, providing a long-term solution for improving antioxidant levels