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10.1080/15440478.2021.1994092 151 ParkJ

A.MainolfiN.SuriV.et al (2019)

Based on their subcellular localization, TLRs are categorized into two major groups: cell surface-localized TLRs (e.g., TLR1, TLR2, TLR4) that act at the plasma membrane, and intracellular TLRs (e.g., TLR7, TLR8, TLR9) that function within endosomal or cytoplasmic compartments ( Figure 3 )