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suppressAfter incubation with Sch A or Sch B for 6 h, RAW264.7 macrophages were further incubated with tested compound-free medium for 16 h for the induction of thioredoxin

Our results clearly highlighted the benefits of these therapeutic interventions

It has been shown that following the intraperitoneal administration of OHP, transient activation of the microglia and the astrocytes in supraspinal areas and the spinal cord is involved in the modulation of pain accompanied by a decrease in the thermal and mechanical pain thresholds [87]

Discussion We report the antitumor activity of R001 against human TNBC in vitro and in vivo, consistent with our previous report of the inhibitory effects against human glioblastoma (GBM) [23]