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Description

Extracellular vesicles as an emerging treatment option for intervertebral disc degeneration: therapeutic potential, translational pathways, and regulatory considerations

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Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ

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High doses of Put (2.5 mM) can induce mild metabolic stress, e.g., by increasing the production of HO as a byproduct of amine oxidation and shifting metabolic pathways towards proline synthesis 66

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Introduction Parkinsons disease (PD) is associated with the selective loss of dopamine (DA) neurons in the substantia nigra pars compacta (SNpc) and DA levels in the corpus striatum of the nigrostriatal DA pathway in the brain

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