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: The FDA removed 12 peptides including BPC-157, TB-500, KPV, and MOTS-C from Category 2 (substances prohibited from compounding) due to original nominators withdrawing their submissions

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The pertinent findings of this study are: 1) enhanced hepatic de novo serine synthesis is required for SAAR to improve glucose tolerance, 2) concurrent with transcriptional activation, a serine synthesis-GSH-lysine lactoylation feedback loop may underlie the increased hepatic serine synthesis in response to SAAR, and 3) hepatic serine synthesis is not necessary for the SAAR-mediated decline in adiposity and liver triglycerides